TimingCoQ10

Best in the morning

When to take CoQ10

Morning or midday, with a fat-containing meal

CoQ10 is a fat-soluble compound your cells use to make energy, and levels fall with age and with statin use. It needs dietary fat to absorb, so take it with a proper meal.

Updated 2026-10-25

Best time in your day

  1. Wake
  2. Workout
  3. Breakfast
  4. Lunch
  5. Evening
  6. Workout
  7. Dinner
  8. Walk
  9. Bed
When
Morning or midday
Food
With a meal that contains fat
Typical dose
100–200 mg per day; split doses above 100 mg

How to take it

  1. 1Take it with breakfast or lunch that includes some fat
  2. 2Split larger doses across two meals
  3. 3Choose ubiquinol if you are over 50 or absorb poorly
  4. 4Allow 4–12 weeks for effects

Watch out

If you take warfarin, do not start CoQ10 without your doctor checking your INR.

Keep apart from

  • Warfarin (may reduce its effect)
  • Blood pressure medication (may add to lowering)

Common questions

Should I take CoQ10 if I take a statin?

Statins lower the body's CoQ10. Some people with statin muscle aches try it; ask your doctor.

Why not at night?

Some people report it feels energising and makes sleep lighter.

Ubiquinone or ubiquinol?

Ubiquinone is cheaper and works for most. Ubiquinol is the ready-to-use form and may suit older adults.

Explore further

Sources

  1. NIH Office of Dietary Supplements: Dietary supplements for primary mitochondrial disorders fact sheet for health professionals

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For general education only, not medical advice. Talk to a qualified doctor before starting or changing supplements, especially if you are pregnant, nursing or on medication.