TimingNiacinamide

Take with meals

When to take Niacinamide

With food

Niacinamide is a form of vitamin B3 that doesn't cause a flush. It's used for skin health and taken with food.

Updated 2026-10-25

Best time in your day

  1. Wake
  2. Workout
  3. Breakfast
  4. Lunch
  5. Evening
  6. Workout
  7. Dinner
  8. Walk
  9. Bed
When
With meals
Food
With food
Typical dose
500 mg once or twice daily (as used in skin studies)

How to take it

  1. 1Take it with food
  2. 2Don't confuse it with niacin
  3. 3Use it for 3–12 months
  4. 4Get liver tests if you take high doses long term

Watch out

Very high doses can affect the liver. Niacinamide doesn't lower cholesterol the way niacin does.

Keep apart from

  • Carbamazepine and primidone

Common questions

Niacin or niacinamide?

Niacin flushes and affects lipids; niacinamide doesn't flush.

Is it the same as in skincare?

Same molecule; oral doses work differently.

Who uses 500 mg twice daily?

It was studied in people at high risk of skin cancer.

Explore further

Commonly used for

Sources

  1. NIH Office of Dietary Supplements: Niacin fact sheet for health professionals

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For general education only, not medical advice. Talk to a qualified doctor before starting or changing supplements, especially if you are pregnant, nursing or on medication.