TimingTMG
Best in the morning
When to take TMG
Morning, with food
TMG (betaine) donates methyl groups and helps lower homocysteine. It's commonly taken with food in the morning.
Best time in your day
- Wake
- Workout
- Breakfast
- Lunch
- Evening
- Workout
- Dinner
- Walk
- Bed
- When
- Morning, with breakfast
- Food
- With food
- Typical dose
- 500–3,000 mg per day
How to take it
- 1Start with 500 mg
- 2Take it with breakfast
- 3Check homocysteine if that's your reason for taking it
- 4Keep the dose moderate
Watch out
Doses of several grams per day may raise LDL cholesterol, so monitor lipids if you take a lot.
Common questions
Why with NMN?
Some people add TMG to replace methyl groups used when making NAD+. Evidence is theoretical.
Does it help workouts?
Some studies show small gains in power at 2.5 g per day.
Is it the same as betaine HCl?
No. Betaine HCl is a stomach acid supplement.
Explore further
More timing guides
TMG with other supplements
Commonly used for
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Build my routineFor general education only, not medical advice. Talk to a qualified doctor before starting or changing supplements, especially if you are pregnant, nursing or on medication.